Soft, light and provides very good insulation. Wool clothes can keep the body warm even in extreme conditions.
Muffalo wool is acquired by shearing tamed muffalos - each muffalo can be sheared every 25 days for 100 wool, for an average of 4 per day.
It can also be purchased from traders.
Muffalo wool has the second worst protective stats of any textile in the game tied only other wools, and besting cloth only by virtue of proving a significantly more heat armor, though still little in compared to textiles like Devilstrand. Like other wools however, where muffalo wool excels is in cold insulation, offering the 4th best cold insulation of any textile in the game. In comparison, its heat insulation is lacking at 19th of all textiles.
Thus, it is almost entirely irrelevant as protective clothing. Additionally, its poor heat insulation make it unattractive in hot biomes, except where bulk textiles of any sort are the primary requirement. Only its cold insulation provides utility in cold biomes, and in many of them other less insulative but more protective textiles will suffice. However, its ease of production and good insulation can make muffalo wool parkas or skin-layer apparel an easy way to provide winter clothing to a colony, and possibly sufficient to avoid sacrificing any other aspects of their outfit. Compared to other wools, which largely fill the same niche, muffalo wool one of the better options, despite production being more costly with muffalo having the slowest Per Day production rate, while eating more than sheep and alpacas. This is due to muffalo wool's exceptional cold insulation - if any wool is being used it is likely because of that cold insulation and the only wool better at that is megasloth wool sheared from the significantly harder-to-a-maintain megasloth. Thus muffalo wool leans into its primary use case heavily.
For use in furniture, it only has a somewhat improved beauty factor over other common textiles, but its rapid redundancy as clothing, the ease of acquisition, and modest but not insignificant value makes it a solid choice for improving furniture beauty and providing bulk textiles for construction. If wool production is being acquired for this purpose however, the fast production rates of sheep, alpaca or megasloth wool, or the lack of a tame maintenance requirement for sheep may be more advantageous if the option is available. Care should be taken as, like other wools in RimWorld, it is exceptionally flammable.