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A fine white powder snorted to produce a euphoric high. Yayo reduces the user's need for rest, and suppresses pain. It is, however, addictive.

DrugHard Drug
Stack Limit

Base Stats

Deterioration Rate
Market Value
Max Hit Points
Work To Make

Stat Modifiers

Yayo is a drug of 1% addiction rate that can be produced at a drug lab with 8 psychoid leaves after researching Psychite refining. Consumption provides +80% to recreation and will generate the Feeling pumped! Let's do this! thought which has a +35 mood effect and affects the body with:

  • Moving: +15%
  • Improves joy 80%
  • Suppresses pain x50%
  • Reduces need for rest by 66%

Those with visible tolerance to psychite, will develop chemical damage in the kidneys in a mean time of 120 days.


Yayo can be manufactured at a drug lab for 8 psychoid leaves. Its synthesis speed is dependent on the Intellectual skill.

Withdrawal Symptoms

Like Flake and Psychite tea, Yayo can cause psychite addiction. Withdrawal lasts for 30 days and causes the following symptoms:


Yayo is one of three drugs that can be produced from psychoid leaves, the others being flake and psychite tea. Yayo can also be further refined into go-juice with the addition of 2 neutroamine.


For use as a drug, yayo is far preferable to flake, with stronger effects and only one fifth as addictive (1% vs 5% addictiveness). Psychite tea is considerably weaker, but much less addictive, than both and is thus a significantly safer option than either. This makes tea more useful for regular use, while yayo is more appropriate for mood emergencies. Though there is no minimum tolerance to get addicted to Yayo, it still contributes to tolerance to Psychite tea.


On the market, yayo is worth 50% more silver than flake, with a 20% increase in the Work To Make and a 100% increase in ingredient cost. The most economical option depends on which is the greater bottleneck: converting the leaves to the drug, or producing the leaves in the first place.

If converting the leaves into drugs is the bottleneck then there are two options. The psychoid leaves could be turned into yayo, however converting as much as possible to flake and then selling the remaining psychoid leaves themselves is even more efficient. For example, a pawn requires 35,000 ticks (9.72 mins) of work and 800 psychoid leaves to synthesize 100 yayo worth Silver 2100. With the same amount of work, a pawn could craft 140 flake worth Silver 1960 and consume 560 of the 800 psychoid leaves. The remaining 240 psychoid leaves are worth Silver 456 for a total of Silver 2416. This is not without its downsides however - fewer traders accept psychoid leaves than accept drugs and without refrigeration, the leaves will eventually rot away. Thus, if the player is likely to caravan to a settlement or receive a relevant trader before they rot entirely away, or can accommodate the refrigeration of leaves long term, converting to flake and selling the remainder of leaves is ideal. If they cannot, converting to yayo for storage may be necessary. If psychoid leaf production is the bottleneck and there is insufficient leaf supply to fully occupy your drug synthesizers' time, producing flake is the optimum as it produces more value per leaf at the cost of more work.

If caravan weight is a limiting factor, yayo is worth more proportional to mass, however the low weight of all the options mean this is unlikely to be relevant as a single muffalo can carry almost 20 stacks of flake worth over 20,000 silver.

Psychite tea is economically inferior to both; its only potential advantage is that it may be used safely by your colonists if scheduled. It is also produced at a campfire or stove with the Cooking skill instead.

Version History

  • 1.2.2719 - Reduced yayo new addiction chance from 10% to 1%, and removed the min tolerance to addict.