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<includeonly>''Main Article: [[Plague]]''</includeonly>The '''Plague''' is a [[Death|deadly]] [[disease]] that affects both humans and animals. It progresses at a fast rate, killing untreated creatures within days from discovery. It can be caught in any [[Biomes|biome]].
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<includeonly>''Main Article: [[Plague]]''</includeonly>
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__NOTOC__
  
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==Overview==
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The Plague is a deadly [[disease]] that progresses at a fast rate, killing untreated colonist in merely 1.5 day from discovery. It also causes +85% whole body pain with -20 mood penalty [[Thoughts#Pain.23In_shock_from_exceptional_pain|''AAAAAHHH! Kill me now!'']], together with -5 mood penalty from the standard [[Thoughts#Sick|''I don't feel very well, I'm sick.'']] thought. It can be caught in any biome randomly.
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{{TOCright}}Plague is a disease that is rapidly fatal for humans. If left untreated, it kills in 1.5 days, but rest and good treatment can slow the disease to the point where it takes 3 days to kill. It takes around 2.121 days to develop immunity to the plague - assuming the affected colonist is rested in an ordinary bed for the whole time, has normal blood filtration, is well-fed, and under the age of 40. Animals are more resistant to the disease, but still need treatment.
 
  
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A skilled doctor, medicine, and healthy [[Blood Filtration]] organs ([[kidney]]s and [[liver]]) are critical to survival. The bonus [[Immunity Gain Speed|immunity gain speed]] could mean the difference between life and death.  
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Requires a skilled doctor and medicine critical to survival. The bonus [[Immunity Gain Speed|immunity gain speed]] could mean the difference between life and death. Good treatment can slow the disease to the point where it takes 30 days to kill. It takes around 2.121 days to develop immunity to the plague; assuming the affected colonist is rested in an ordinary bed for the whole time, has normal blood filtration, is well-fed, and under the age of 40.
  
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=== Prevention ===
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[[Blood Filtration]] organs should be replaced early on before catching any disease, as it might be too late to operate someone already sick.
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[[Penoxycyline]] prevents colonists from falling sick to the Plague, but does nothing to stop an infection already in progress.
 
  
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== Stages ==
 
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Extreme (Initial) and Extreme (Advanced) both display as just "Extreme" ingame, but have different symptoms.
 
  
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====Minor====
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== Defeating the Plague ==
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* {{++|20%}} [[Pain]]
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* {{--|5%}} [[Consciousness]]
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Ensure the afflicted get as much bed rest as possible by prioritizing 'Rest until Healed' and get them the best medical treatment available.
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* {{--|5%}} [[Manipulation]]
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[[Penoxycyline]] prevents colonists from falling sick to the plague but does nothing to stop an infection already in progress, as of Alpha 17.
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=== Treating Normal People (<40 Years Old) ===
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You need at least 40%+ average treat quality to slow the Plague's progression down sufficiently so that it doesn't kill the victim.
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The following combinations of doctoring skill and medicine are capable of achieving 40% treatment quality (assuming a perfectly healthy, unmodified doctor, the patient is rested and well-fed at all times, below the age of 40, and treatment is administered immediately) - you'll generally want to aim above these thresholds for safety though; these combinations are just the bare minimum required, and aren't guaranteed to work out:
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*Level 1 Medicine skill and [[glitterworld medicine]]
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*Level 4 Medicine skill and standard [[medicine]]
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*Level 8 Medicine skill and [[herbal medicine]]
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=== Treating the Elderly (80+ Years Old) ===
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It's notably more difficult to treat the elderly as they only gain immunity at 80% of the standard rate - unless they have improved blood filtration. Your doctors will need to be capable of administering an average of 65%+ treatment quality in order for your elderly to survive. Again, this is the bare minimum figure and doesn't take into account the time to reach the medicine and the patient - so you'll generally want to aim above this.
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The following combinations of doctoring skill and medicine type are capable of administering 65% treatment quality:
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*Level 3 Medicine skill and glitterworld medicine
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*Level 8 Medicine skill and standard medicine
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*Level 15 Medicine skill and herbal medicine
  
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====Major====
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If high quality treatment is not available, consider administering [[luciferium]] to the patient, which will dramatically boost their blood filtration and thus rapidly achieve immunity.
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* {{++|35%}} [[Pain]]
 
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* {{--|20%}} [[Consciousness]]
 
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* {{--|20%}} [[Manipulation]]
 
  
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====Extreme (Initial)====
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== Stages ==
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* {{++|60%}} [[Pain]]
 
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* {{--|30%}} [[Consciousness]]
 
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* {{--|30%}} [[Manipulation]]
 
  
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====Extreme (Advanced)====
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These are the following stages in which the Plague will progress through, and the effects it has on the victim:
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* {{++|85%}} [[Pain]]
 
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* {{--|30%}} [[Consciousness]]
 
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* {{--|30%}} [[Manipulation]]
 
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* {{--|15%}} [[Breathing]]
 
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* [[Death]] at 1 severity.
 
  
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== Progression ==
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'''Minor (Hidden) - Severity: 0.01 - 0.39'''
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===Stages===
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*No effects on the affected colonist
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This disease is detected immediately. Severity goes up over time, and is slowed by treatment until immunity is reached.
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*Buildup to the initial 40% disease head start that the plague has
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*Minor - Severity: 0 - 0.59
 
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*Major - Severity: 0.6 - 0.79
 
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*Extreme (Initial) - Severity: 0.8 - 0.9
 
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*Extreme (Advanced) - Severity 0.91 - 0.99
 
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*Death - Severity 1
 
  
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===Humans===
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'''Minor - Severity: 0.4 - 0.59'''
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*When not immune, severity increases by 0.666 per day.
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*+20% Pain
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*When immune, severity decreases by 0.333 per day.
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*-5% Consciousness
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*Immunity increases by 0.5224 per day when sick.
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*-5% Manipulation
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*Treatment slows progression by a maximum of 0.3628 per day.
 
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**This means the disease will progress by 0.3032 per day at 100% tend quality.
 
  
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===Animals===
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'''Major - Severity: 0.6 - 0.79'''
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Animals can face the same disease, but their immunity increases faster, and treatment slows progression more.
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*+35% Pain
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*When not immune, severity increases by 0.666 per day.
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*-20% Consciousness
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*When immune, severity decreases by 0.333 per day.
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*-20% Manipulation
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*Immunity increases by 0.6092 per day when sick.
 
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*Treatment slows progression by a maximum of 0.4254 per day.
 
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**This means the disease will progress by 0.2406 per day at 100% treatment.
 
  
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== Treatment ==
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'''Extreme (Initial) - Severity: 0.8 - 0.9'''
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Ensure the afflicted pawns get as much bed rest as possible by prioritizing 'Rest until Healed', and get them the best medical treatment available. For humans, treatment is administered once every 15 hours. For animals, treatment is administered every 48 hours (2 days).
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*+60% Pain
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*-30% Consciousness
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*-30% Manipulation
  
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On a constantly resting, well-fed pawn with 100% [[Immunity Gain Speed]], you'll need at least 15% average treatment quality to slow the plague's progression down sufficiently so that it doesn't kill the victim.
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'''Extreme (Advanced) - Severity 0.91 - 1'''
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*+85% Pain
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*-30% Consciousness
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*-30% Manipulation
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*-15% Breathing
  
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=== Vulnerable ===
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=== Progression ===
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For humans with a base [[Immunity Gain Speed]] of 47% or less, there is no chance that they will be able to survive the plague normally, even with 100% treatment quality for all treatments and rest in a [[hospital bed]] with [[vitals monitor]] connected. This includes very old people over the age of 120, and some people with kidney and liver damage (physical or chemical). A colonist with poor rest or treatment quality may also be on the verge of death.
 
  
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To save a colonist on verge of death, you can do the following:
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*When not immune, severity increases by 0.4 per day.
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*Administer [[healer mech serum]] - instantly treats the disease
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*When immune, severity decreases by 0.2 per day.
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*Administer [[luciferium]] - if pawn has 28% or more immunity gain speed remaining initially, this gives pawn a chance to survive
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*Immunity increases by 0.3 per day when sick.
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*Use the medic cycle of the [[Biosculpter pod]]{{IdeologyIcon}} - if used early enough, the pawns can bring themselves to it
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*Treatment slows progression by a maximum of 0.38 per day.
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**This means the disease will progress by 0.02 per day at this rate.
  
 
<noinclude>{{Nav/disease}}</noinclude>
 
<noinclude>{{Nav/disease}}</noinclude>
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[[Category:Disease]]
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[[Category: Disease]]

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