Editing Disease

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<includeonly>:''Main article: [[Disease]]''</includeonly>{{About|treatable illnesses|physical damage|Injury|chronic health conditions|Ailments}}

'''Diseases''' are temporary and treatable ailments, that pass away after a certain amount of time or treatment.

== Contract ==
Most diseases are contracted as part of an [[event]]. Your colony's [[biome]] determines how common diseases are, as well as how common each disease is. However, some diseases happen situationally, regardless of biome:
*[[Infection]] may occur after a bleeding [[injury]], burn, or frostbite is inflicted. Tending the injury in a clean room reduces the chance of infection.
*[[Lung rot]] occurs randomly when inhaling enough [[rot stink]].
*[[Blood rot]]{{RoyaltyIcon}} and [[paralytic abasia]]{{RoyaltyIcon}} are exclusively part of [[quest]]s, while [[infant illness]]{{BiotechIcon}} can only happen during [[Reproduction#Birth|birth]].

Note that diseases are '''not contagious''' in RimWorld. Disease does not ever spread between colonists, though disease events often simulate "outbreaks" by inflicting multiple colonists at the same time.

The drug [[penoxycyline]] protects against [[Malaria]], [[Plague]], and [[Sleeping sickness]]. The disease event still happens, but colonists will not be affected.

== Summary ==
Humans and animals can get diseases. Most diseases uses the ''severity'' mechanic. As a disease progresses, its symptoms progressively get worse. If a fatal disease's severity reaches 1.0 (100%), then [[death]] occurs. Most diseases go from minor -> major -> extreme. How fast a disease progresses depends on the disease itself.

== Diseases ==
'''Note:''' Base values of severity and immunity gain speed used in the table.<br>Treatment's reduction of severity depends on tend quality. 50% tend quality equals half the reduction.
<div><li style="display: inline-table;">
{| {{STDT| c_10 text-left}}
|-
! Disease!! Fatal? !! Description !! Severity !! Treatment 
|-
| [[Infection]] || {{Check}} || Generic infection of individual [[injury|wounds]]. 
*Fast moving and dangerous. 
** < 1.25 days to kill if untreated. <1.5 days for immunity.
*Mild symptoms until extreme severity (>0.87). ({{++|5%}} to {{++|12%}} pain) 
|
* Severity: +0.84 / day
* Immunity: +0.644 / day
* Treatment: -0.53 severity / day <br>(at 100% quality)
| 
* Bed rest and medicine
* Amputation of infected body part
|-
| [[Flu]] || {{Check}} ||  ''Relatively'' mild and common disease.
*Non-elderly adults can survive without treatment, with just bedrest.
*Lowers [[consciousness]], [[manipulation]], [[breathing]] ({{--|5%}} to {{--|20%}}).
|
* Severity: +0.249 / day
* Immunity: +0.239 / day
* Treatment: -0.077 severity / day <br>(at 100% quality)
| 
* Bed rest and medicine
|-
| [[Malaria]] || {{Check}} || Common in tropical [[biomes]].
* Attacks [[blood filtration]], slowing immunity speed.
* Later stages cause [[pain]] and reduces [[consciousness]].
| 
* Severity: +0.370 / day
* Immunity: +0.314 / day
* Treatment: -0.232 severity / day<br>(at 100% quality)
| 
* Bed rest and medicine
|-
| [[Plague]] || {{Check}} || Fast moving and ''extremely'' painful.
* ~1.5 days to kill if untreated.
*Constant [[pain]] ({{++|20%}} to {{++|85%}}).
*Also reduces [[consciousness]] and [[manipulation]] (up to {{--|30%}}).
||
* Severity: +0.666 / day
* Immunity: +0.522 / day
* Treatment: -0.362 severity / day <br>(at 100% quality)
|
* Bed rest and medicine
|-
| [[Sleeping sickness]] || {{Check}} || Very slow-moving infection. Native only to [[biome|rainforests and swamps]].
*Relatively easy to treat if rested. 
* Threat is the amount of rest / medicine required.
*Mainly lowers [[consciousness]] & [[manipulation]] ({{--|2%}} to {{--|20%}}).
||
* Severity: +0.12 / day
* Immunity: +0.11 / day
* Treatment: -0.07 severity / day <br>(at 100% quality)
| 
*  Bed rest and medicine
|-
| [[Scaria]] || {{Check}} || Drives [[animal]]s to become [[manhunter]]s. 
*Exclusive to animals in [[manhunter pack]]s. 
*Humans and colony animals immune.
||
* Kills in 5 days, unless cured
| 
* Surgery
**{{icon small|medicine}} 3 [[medicine]]
**[[Skills#Medical |Medical Skill]] 8+
|-
| [[Lung rot]] || {{Check}} || 
Occurs after enough exposure to [[rot stink]]. Avoid rot stink to avoid.
* Resisted by sources of [[Toxic Environment Resistance]].
* Easily treatable overall. Can drain medicine.
* Impairs [[breathing]] slightly. Minimal symptoms overall.
||
* Severity: +0.300 / day
* Treatment: -1.000 severity / day <br>(at 100% quality)
|
* Medicine
Resolves from:
*Min {{ticks/gametime|360000}}
*Max {{ticks/gametime|480000}}
|-
| [[Gut worms]] || {{cross}} || Doubles hunger rate.
*Also painful ({{++|20%}} pain).
|| 
* No progression
* Cured at 300% total Tend Quality
|
* Medicine (48hr per tend)
* Stomach replacement or removal
|-
| [[Muscle parasites]] || {{cross}} || Heavily impairs work.
*Significant tiredness.
*Lowered [[manipulation]] and [[movement speed]] ({{--|30%}}).
*Also painful ({{++|20%}} pain).
||
* No progression
* Cured at 300% total Tend Quality
| 
* Medicine (48hr per tend)
|-
| [[Fibrous mechanites]] || {{cross}} || Very long-lasting, but ''improves'' working.
*Painful, significant tiredness.
*Significantly increases [[manipulation]], [[movement speed|moving]] and [[blood pumping]] ({{+|50%}} to all).
||
* Severity: +0.25 / day
* Treatment: -1.00 severity / day <br>(at 100% quality)
| 
* Medicine
**Prevents pain increase only
Resolves from:
*Min {{ticks/gametime|900000}}
*Max {{ticks/gametime/days|1800000}}
|-
| [[Sensory mechanites]] || {{cross}} || Very long-lasting, but ''improves'' many stats.
*Painful, significant tiredness.
*Significantly increases [[sight]], [[hearing]], and [[talking]] ({{+|50%}} to all).
*Increases [[manipulation]] ({{+|30%}}).
||
* Severity: +0.25 / day
* Treatment: -1.00 severity / day <br>(at 100% quality)
| 
* Medicine
**Prevents pain increase only
Resolves from:
*Min {{ticks/gametime|900000}}
*Max {{ticks/gametime/days|1800000}}
|-
| [[Organ decay]] || {{Check}} || No natural cure. Only targets specific organs.
*Causes increasingly worse pain and weakened part efficiency of the afflicted organ, ultimately destroying it at 1 severity.
*Only treatable by replacing the organ.
*Only targets the heart, lungs and kidneys.
*Can appear rarely as a disease event, or on [[Creepy joiner]]s.{{AnomalyIcon}}
||
* Severity: +0.0166 to 0.0334 / day
| 
* Replacing the organ
**Does not affect bionic or prosthetic organs
Reaches max severity after:
*Min {{ticks/gametime|1800000}}
*Max {{ticks/gametime/days|2400000}}
|-
| [[Blood rot]]{{RoyaltyIcon}} || {{Check}} || ''Extremely'' long lasting blood affliction.
*[[Quest]] only.
*Mild and easily treated, but can be a drain on medicine.
||
* Severity: +0.40 / day
* Treatment: -1.00 severity / day <br>(at 100% quality)
|
* Medicine
* Surgery for immediate cure
**{{icon small|Glitterworld medicine}} 10 [[glitterworld medicine]]
**[[Skills#Medical |Medical Skill]] 5+
Resolves from:
* Min {{ticks/gametime/days|60000*30}}
* Max {{ticks/gametime/days|60000*40}}
|-
| [[Paralytic abasia]]{{RoyaltyIcon}} || {{Cross}} || Complete immobility. ''Extremely'' long lasting.
*[[Quest]] or [[Events#Transport pod crash|transport pod crash]] only.
||
* No progression
* 1% per day to instantly cure
|
* Waiting
* Surgery for immediate cure
**{{icon small|Glitterworld medicine}} 10 [[glitterworld medicine]]
**[[Skills#Medical |Medical Skill]] 5+
Always resolves after:
* Min {{ticks/gametime/days|60000*30}}
* Max {{ticks/gametime/days|60000*40}}
|-
| [[Infant illness]]{{BiotechIcon}} || {{Check}} || Inflicted after a sick [[Reproduction#Birth|birth]] of a [[baby]].
*4 different types of illness, from mild to grave. Switches every 1-3 days.
*Uniquely, reducing severity to 0 cures the disease (no immunity required).
||
* Starts as Major severity (0.40)
* Severity gain depends on the type
** From -0.25 to +0.5 severity / day
* Immunity: +0.10 / day
* Treatment: -0.35 severity / day <br>(at 100% quality)
| 
* Medicine and bed rest
|-
|}
</li><div>

== Treatment ==
Most diseases can be tended to, just like an [[injury]] or [[ailment]], by a [[Doctoring|Doctor]] pawn and when the afflicted pawn is assigned to [[Work|Patient]] themselves. Tend Quality is determined by a variety of factors, including the doctor's [[skill]] and the quality of [[Medicine]] used. Generally, higher quality tends reduce the total time until recovery, though mechanics vary. How often a disease can be tended depends on the disease itself.

There are 3 types of diseases to tend to:
* The disease will progress over time, and treatment slows down progression. Immunity is gained over time, dependent on [[Immunity Gain Speed]] and independent of tend quality. Once immune, the disease will slowly fade and the colonist will stop being a patient. This applies to most fatal diseases, including the [[flu]], [[infection]], and [[plague]].
* The disease does not progress. Treatment must reach a ''total tend quality'' (300%) before the disease is cured. For example, 4 tends at 80% quality would equal 320% total tend quality. Applies to [[gut worms]] and [[muscle parasites]].
* The disease progresses over time, and treatment slows and even prevents progression. The disease fades only after a certain time. Applies to [[lung rot]], [[fibrous mechanites]], [[sensory mechanites]], and [[blood rot]].{{RoyaltyIcon}}

Certain diseases have specialized cures. For example, [[infection]] in a non-vital part can be cured by amputating or [[Artificial body part|replacing]] a limb, [[blood rot]] can be instantly cured with [[glitterworld medicine]], and [[gut worms]] can be treated by replacing the stomach. In addition, a [[healer mech serum]] immediately cures any disease.

=== Immunity gain ===
{{Main|Immunity Gain Speed}}
Some diseases are a race between the increasing severity of the disease and the increasing immunity to it. This immunity gain is controlled by several factors:
* Base immunity gain speed for the particular disease. 
* InfectionLuck, an uncontrollable generated value that adds randomness to the diseases progression. Each disease has a variance in Immunity gain speed of 20% up or down. 
* The [[Immunity Gain Speed]] stat of the patient

Immunity Gain Speed is affected by the following:
* '''[[Food]]''': Pawns above 12.5% [[Saturation]] do not have any penalties to immunity.
* '''[[Rest]]''': Actively resting gives a bonus to speed. Resting in any [[bedroll]] or [[bed]] increases the stat, a [[hospital bed]] increases it further, and a hospital bed with an attached [[vitals monitor]] increases it the most.{{Check Tag|Verify|Does this affect their IGS stat or does it affect their immunity they actually gain only?}}
* '''Age''': As a pawn gets closer to and past their species' life expectancy, immunity gain speed decreases. 
** For baseline humans, immunity gain speed is gradually lost after age 54. [[Genes]]{{BiotechIcon}} like [[Genes#Mild cell instability|cell instability]] can affect the pawns lifespan and, in turn, affect this progression.{{Check Tag|Verify|Verify and also confirm on Immunity Gain Speed page}}
* '''[[Blood Filtration]]''': Mostly increased via [[luciferium]]. Reduced with [[kidney]] or [[liver]] damage, slightly improved with a [[detoxifier kidney]]{{BiotechIcon}}.
* '''Direct boosts''': The [[Super-immune]] trait, [[Immunoenhancer]]{{RoyaltyIcon}}, and [[gene]]s{{BiotechIcon}} can increase immunity speed.

Note that these only apply to diseases with immunity mechanics. For example, you don't need to give a pawn with [[gut worms]] bedrest.

== Disease frequency ==

=== Disease frequency by AI storyteller ===
Disease frequency is controlled directly by the [[AI_Storytellers#Disease frequency|Disease frequency]] AI storyteller setting. 

This value can be changed in custom storyteller settings, but has the following default values by difficulty:

{| {{STDT| c_08 text-center}}
! Difficulty !! Disease interval multiplier
|-
| Peaceful || 3
|-
| Community builder || 2.5
|-
| Adventure story || 1.3
|-
| Strive to survive || 1.0
|-
| Blood and dust || 0.95
|-
| Losing is fun || 0.9
|-
|}

=== Disease frequency by [[biomes]] ===
{{stub|section=1|reason = Use [[Biomes]] as references but playtest against the last version or just inspect source code and resource files.}}

== Version history ==
* [[Version/0.7.581|0.7.581]] - Added with flu, plague, malaria, sleeping sickness.
* [[Version/0.9.722|0.9.722]] - Diseases can now cause vomiting.

[[Category:Health]]
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