Editing Ailments

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{{rewrite|reason=Cleanup and standardization needed - treatment and stages sections for each required. See [[Template:Heal Option Table]]}}
{{About|chronic health conditions|physical damage|Injury|treatable illnesses|Disease}}
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'''Ailments''' are [[health]] conditions that cannot be treated completely using medicine alone. 

"MTB" stands for "Mean Time Between", and is how it's presented in the game files.

Some conditions can give rise to other conditions; the risk of this happening will diminish if the condition is treated.

Most permanent ailments are curable with body part replacements or usage of the [[healer mech serum]].

{{Heal Option Table}}

== Chronic ==
Ailments that come with age. Either non-fatal, or progresses extremely slowly towards fatality compared to infectious diseases.

=== Alzheimer's ===
{{stub|reason = "Forget memory" and "confused wandering" mechanics}}
A brain disease usually associated with aging. Alzheimer's disease causes progressive degradation in the ability to think and remember. Patients are known to forget close relatives and sometimes wander around in confusion.

Alzheimer's progresses by 0.003 per day, meaning that it will take 333.33 days for it to reach full severity from when it first appears.

{| class="wikitable"
|-
! Stage !! Begins at !! Symptoms
|-
| '''Alzheimer's (minor)''' || ≥0% severity ||
* -5% part efficiency
* Confused wandering (''MTB of 12 days'')
* Forget memory (''MTB of 7 days'')
|-
| '''Alzheimer's (minor)''' || ≥20% severity ||
* -10% part efficiency
* Confused wandering (''MTB of 9 days'')
* Forget memory (''MTB of 4 days'')
* ''0.15%'' of conditional thoughts nullified
|-
| '''Alzheimer's (major)''' || ≥50% severity ||
* -15% part efficiency
* Confused wandering (''MTB of 7 days'')
* Forget memory (''MTB of 2 days'')
* ''0.5%'' of conditional thoughts nullified
|-
| '''Alzheimer's (major)''' || ≥80% severity ||
* -20% part efficiency
* Confused wandering (''MTB of 4 days'')
* Forget memory (''MTB of 0.8 days'')
* ''1%'' of conditional thoughts nullified
|}

A human pawn can first get Alzheimer's at age 34.
{| class="wikitable"
|-
! Alzheimers chance
|-
| {{GraphChart
|width=400
|height=100
|type=line
|x=0, 33.6, 56, 72, 80, 120
|y=0, 0, 0.061, 0.12, 0.2, 0.3 
|xAxisTitle = Pawn age (years)
|yAxisTitle = Chance/Birthday (%)
}}
|}

'''Treatment:'''
* [[Luciferium]]: Luciferium removes one randomly selected condition that it can cure every 900,000 to 1,800,000 [[ticks]] (15 - 30 in-game days). Having fewer luciferium-curable conditions will increase the chance that Alzheimer's is chosen, so it can be worth attempting to address any conditions that can be other means. Even with this however, it can take a significant amount of time. Also note that luciferium is a permanent decision - once taken, further doses are necessary to avoid madness and death. 
* [[Healer mech serum]]: A healer mech serum will instantaneously heal one condition of the pawn, including Alzheimer's. Which condition is chosen depends on a priority order, with Alzheimer's being a moderately high priority. See the serum's [[Healer_mech_serum#Order_of_conditions_treated|condition order]] for details.
* [[Resurrector mech serum]]: Because the resurrector mech serum will replace a destroyed head with a healthy one, it can be used to heal brain ailments, including Alzheimers. Consistently destroying the head can be difficult. With the [[Ideology DLC]], extracting the [[skull]] from a dead pawn will do this reliably and safely, but without it, the best way is allowing colonists or animals to eat sections of the corpse, at the risk of consuming the entire body and permanently losing the pawn. Furthermore, no matter how successful the head removal, there is always the risks normally associated with resurrection, including [[dementia]], [[blindness]], and [[resurrection psychosis]]. Note that pawns will initially be incapacitated due to resurrection sickness.

=== Asthma ===
A chronic health condition where inflammation causes the airways to narrow, restricting the flow of oxygen to the lungs. Unlike other chronic diseases, asthma can be contracted at almost any age, meaning it's not terribly uncommon to have an asthmatic person some time down the line.

When not treated, it progresses by a rate of 0.25 per day, meaning it will take 2 days to reach full severity (50%).

Good treatment will reduce the rate of progression by up to 0.8, meaning it will regress by 0.55 a day; it can be returned to its initial severity, but cannot be cured completely.

Asthma's severity will fluctuate depending on the quality of treatment received, with a treatment quality of 32% beginning to regress the stages of asthma (the higher, the better).

{| class="wikitable"
|-
! Stage !! Begins at !! Symptoms
|-
| '''Asthma (minor)''' || ≥ 0% severity  || -10% part efficiency
|-
| '''Asthma (major)''' || ≥ 30% severity || -30% part efficiency
|-
| '''Asthma (major)''' || ≥ 45% severity || -50% part efficiency
|}

Treatment:
* The severity of asthma can be reduced with treatment, which can be given every 420,000 ticks (around 7 days). One treatment applies to both lungs.
* Asthma can be cured by replacing each affected lung with a [[Lung#Acquisition|healthy replacement]].

A human pawn can first get asthma at any age.
{| class="wikitable"
|-
! Asthma chance
|-
| {{GraphChart
|width=400
|height=100
|type=line
|x=0, 16, 24, 40, 120
|y=0, 0.048, 0.096, 0.1344, 0.1344
|xAxisTitle = Pawn age (years)
|yAxisTitle = Chance/Birthday (%)
}}
|}

Asthma can also affect animals, domestic, tamed and wild. Domestic and tamed will notify you that they "need treatment", although there apparently is no downside for ignoring that request except slowing them down which may be bad for [[Animals#Training|trained]] or [[pack animal]]s. Similarly, asthmatic wild animals on the map can roam and eat indefinitely without treatment. In fact, wild animals with asthma are easier and slightly safer to hunt, because asthma will reduce their [[move speed]] to 81%, and their [[manipulation]] to only 90%, which makes any counter-attack less effective.

=== Bad back ===
Degradation in the spinal column and surrounding musculature. This makes it hard to move and bend smoothly.

{| class="wikitable"
|-
! Ailment !! Symptoms
|-
| '''Bad back''' || 
* -30% [[Moving]]
* -10% [[Manipulation]]
|}

A bad back can be cured by installing a [[bionic spine]], or with the use of [[biosculpter pod]]'s bioregeneration cycle{{IdeologyIcon}}.

A human pawn can first get a bad back at age 41.
{| class="wikitable"
|-
! Bad back chance
|-
| {{GraphChart
|width=400
|height=100
|type=line
|x=0, 40, 50, 60, 70, 80, 120
|y=0, 0, 0.93, 1.395, 1.395, 1.86, 1.86
|xAxisTitle = Pawn age (years)
|yAxisTitle = Chance/Birthday (%)
}}
|}

=== Cataract ===
Milky-looking opacity in the eye. Cataracts impair vision.
{| class="wikitable"
|-
! Ailment !! Symptoms
|-
| '''Cataract''' || -50% part efficiency in the affected eye. This results in 50% [[sight]] if both eyes are affected.
|}
Cataracts can be cured through the following methods:
* Replacing the affected eyes with a [[bionic eye|bionic]] or [[archotech eye|archotech]] eye.
* Use of a [[healer mech serum]] which will heal cataracts in both eyes at once
* Via [[luciferium]] use. Note that this does not occur instantaneously, but instead at healing instances that occur periodically. See that page for details.
* Through the use of the [[biosculpter pod]]'s bioregeneration cycle.{{IdeologyIcon}}
* Via the [[Scarless]] gene.{{BiotechIcon}} Note that this does not occur instantaneously, but instead at healing instances that occur periodically. See that page for details.

A human pawn can first get a cataract at age 49.
{| class="wikitable"
|-
! Cataract chance
|-
| {{GraphChart
|width=400
|height=100
|type=line
|x=0, 48, 60, 70, 120
|y=0, 0, 0.53, 1.1045, 1.1045
|xAxisTitle = Pawn age (years)
|yAxisTitle = Chance/Birthday (%)
}}
|}

=== Carcinoma ===
{{Stub|section=1|reason=How do the stages progress/occur and what chances and factors affects them?}}
A carcinoma (or cancer) is where mutated cells uncontrollably divide to form tumors, which then 'crowd out' normal bodily cells and hinder bodily function in that area. Carcinomas can be surgically removed by a skilled doctor or, in some cases, the affected body part can be removed, either by amputation, transplantation of a healthy body part, or replacement by an [[artificial body part]]. Ordinary treatment will prolong the development of a carcinoma or speed up remission, and can be done by doctors of any skill, though better treatment quality is more effective. 

A carcinoma typically starts out at 30% severity. There is a 30% chance that a carcinoma won't cause any pain whatsoever.

A cancer has 3 stages; growing, stable and remission.
* When growing, it progresses by 0.003 per day, multiplied by a random factor of 0.45 - 1.65.
* When stable, it neither grows nor regresses on its own. 
* When in remission, it regresses by 0.002 per day, multiplied by a random factor of 0.7 - 1.5.

Good treatment can slow progression by 0.0027 per day, meaning that the carcinoma will:
* grow more slowly when in growing stage
:* some slow-growing carcinomas (something less than half)<!-- RE "something less than half" - it's .003 x a random factor from .45-1.65, so anything {< (.003 x .9) < .0027} - BUT can't state that's = 40% (10/25) because we don't know if that random "x .45-1.65" is a straight-line %, or a bell curve, or something else. --> may stop or actually regress (very slowly) during their "growing" stage with good treatment
* slowly regress when stable
* regress quickly when in remission
{| class="wikitable"
|-
! Stage !! Begins at !! Symptoms
|-
| '''Carcinoma (minor)''' || ≥0% severity ||
* Little pain (+10%)
* -10% part efficiency
|-
| '''Carcinoma (minor)''' || ≥15% severity ||
* Moderate pain (+20%)
* -25% part efficiency
|-
| '''Carcinoma (major)''' || ≥40% severity ||
* Moderate pain (+35%)
* -50% part efficiency
|-
| '''Carcinoma (major)''' || ≥60% severity ||
* Acute pain (+50%)
* -80% part efficiency
|-
| '''Carcinoma (extreme)''' || ≥80% severity ||
* Acute pain (+60%)
* -90% part efficiency
|-
| '''Carcinoma (extreme)''' || 100% severity ||
* Affected part is destroyed
|}

Treatment:
* Treated every {{ticks|240000}}
* The carcinoma will disappear if severity reaches 0.
* "Excise carcinoma" surgery; this needs 4 medicine of [[medicine|industrial quality]] or above, {{ticks|4500}} of work, and a doctor with a [[medical]] skill of 10 or above. The surgery only has a 70% base chance to succeed.{{Check Tag|Fact Check|Not in .xml}} Also note that if the surgery fails, there is a 25% chance that the patient [[Death|dies]]. Thus, as the maximum [[Doctoring#Success chance|success chance]] of any surgery is capped at 98%, there is always at least a 0.5% chance of death per attempt.

A human pawn can first get a carcinoma from normal aging at age 23. Carcinomas from other sources, including [[toxic buildup]] and [[nuclear stomach]]s{{RoyaltyIcon}}, can happen at any age. Installed nuclear stomachs create a carcinoma on the torso with an MTB of 120 days.
{| class="wikitable"
|-
! Carcinoma chance
|-
| {{GraphChart
|width=400
|height=100
|type=line
|x=0, 22.4, 80, 120
|y=0, 0, 0.11, 0.15
|xAxisTitle = Pawn age (years)
|yAxisTitle = Chance/Birthday (%)
}}
|}

=== Dementia ===
Dementia is simply the functionality of the brain declining, and affects all cognitive functions.

It can only be healed with [[luciferium]] or a [[healer mech serum]].
{| class="wikitable"
|-
! Ailment !! Symptoms
|-
| '''Dementia''' ||
* Impaired brain function (-15% part efficiency)
** Effectively -15% [[Consciousness]]
* Impaired [[Talking]] (-25%)
** Net loss of 40% [[Talking]] including brain function loss
* Impaired [[Hearing]] (-25%)
** Net loss of 40% [[Hearing]] including brain function loss
* Confused wandering (''MTB of 5 days'')
* Slightly accelerated skill loss
**5% at day 4
**15% at day 12
**25% at day 20
|}

A human pawn can first get dementia from aging at age 69. Dementia from other sources including [[toxic buildup]] can happen at any age.
{| class="wikitable"
|-
! Dementia chance
|-
| {{GraphChart
|width=400
|height=100
|type=line
|x=0, 68, 76, 92, 120
|y=0, 0, 0.93, 9.3, 9.3
|xAxisTitle = Pawn age (years)
|yAxisTitle = Chance/Birthday (%)
}}
|}

=== Frail ===
Generalized loss of muscle and bone density. Note that frail ''can'' stack with bad back.

{| class="wikitable"
|-
! Ailment !! Symptoms
|-
| '''Frail''' || 
* -30% [[Moving]]
* -30% [[Manipulation]]
|}

Can only be cured with [[luciferium]], a [[healer mech serum]], or with the use of [[biosculpter pod]]'s bioregeneration cycle{{IdeologyIcon}}.

A human pawn can first get frail at age 51.
{| class="wikitable"
|-
! Frail chance
|-
| {{GraphChart
|width=400
|height=100
|type=line
|x=0, 50, 60, 70, 120  
|y=0, 0, 1.395, 2.604, 2.604
|xAxisTitle = Pawn age (years)
|yAxisTitle = Chance/Birthday (%)
}}
|}

=== Artery blockage ===
A blockage in one of the critical arteries in the [[heart]]. Heart artery blockages randomly induce [[#Heart attack|heart attacks]]. Artery blockages can be treated by replacing the heart with a [[heart|natural]], [[prosthetic heart|prosthetic]] or [[bionic heart|bionic]] replacement, with a [[healer mech serum]], with [[luciferium]], or with the use of [[biosculpter pod]]'s bioregeneration cycle{{IdeologyIcon}}.

Artery blockages progress by a base of 0.0007 per day, multiplied by a random factor between 0.5 - 3.
This means that artery blockages can take anywhere from 7.9 to 47.6 in-game years from onset to become fatal on its own.

Artery blockages can be treated by replacing the heart.

{| class="wikitable"
|-
! Stage !! Begins at !! Symptoms
|-
| '''Artery blockage (minor)''' || ≥0% severity ||
* -5% part efficiency
* [[#Heart attack|Heart attack]] (''MTB of 600 days'')
|-
| '''Artery blockage (minor)''' || ≥20% severity ||
* -10% part efficiency
* [[#Heart attack|Heart attack]] (''MTB of 500 days'')
|-
| '''Artery blockage (major)''' || ≥40% severity ||
* -15% part efficiency
* [[#Heart attack|Heart attack]] (''MTB of 300 days'')
|-
| '''Artery blockage (major)''' || ≥60% severity ||
* -35% part efficiency
* [[#Heart attack|Heart attack]] (''MTB of 200 days'')
|-
| '''Artery blockage (extreme)''' || ≥90% severity ||
* -60% part efficiency
* [[#Heart attack|Heart attack]] (''MTB of 120 days'')
|-
| '''Artery blockage (extreme)''' || 100% severity ||
* [[Death]]
|}

A human pawn can first get an artery blockage at age 21.
{| class="wikitable"
|-
! Artery blockage chance
|-
| {{GraphChart
|width=400
|height=100
|type=line
|x=0, 20, 24, 40, 80, 120  
|y=0, 0, 0.1, 0.145, 0.16, 0.17
|xAxisTitle = Pawn age (years)
|yAxisTitle = Chance/Birthday (%)
}}
|}

=== Hearing loss ===
Inability to hear quiet sounds due to degradation of hair cells in the cochlea.
{| class="wikitable"
|-
! Ailment !! Symptoms
|-
| '''Hearing loss''' || 
* -50% part efficiency (results in 50% [[hearing]] if both ears are affected)
|}

Can be partially mitigated with one or two [[cochlear implant]]s
Can be completely mitigated with a single [[bionic ear]], even if the other ear remains affected.
A [[Biosculpter_pod|bioregeneration cycle]]{{IdeologyIcon}} can completely cure hearing loss in both ears.

A human pawn can first get hearing loss at age 49.
{| class="wikitable"
|-
! Hearing loss chance
|-
| {{GraphChart
|width=400
|height=100
|type=line
|x=0, 48, 60, 70, 120
|y=0, 0, 0.53, 1.11045, 1.11045
|xAxisTitle = Pawn age (years)
|yAxisTitle = Chance/Birthday (%)
}}
|}

== Acute ==
Some ailments arise as a result of an acute lack of food or exposure to extreme temperatures. These ailments can only be treated by addressing the underlying cause (e.g. providing food or moving to more comfortable temperatures).

=== Malnutrition ===
When a pawn's [[Eating|food]] meter reaches 0%, they will begin to suffer from [[malnutrition]], shown on the health tab. When a colonist is starving they will prioritize eating over other activities, including firefighting and doctoring.

Malnutrition severity without food will advance at an average of 17% per day. There is a variation for each pawn that will vary this by 20% in both directions, meaning a pawn may actually die of malnutrition between 4.9~7.4 days of first having symptoms. There is no stat indicating the specific rate that a pawn may die of malnutrition, but the modified rate is determined for each specific pawn in a given playthrough. 
{| class="wikitable"
|-
! Stage !! Usually Begins at !! Symptoms
|-
| '''Malnutrition (trivial)''' || 0.0 days since hunger hit zero ||
* -5% [[consciousness]]
* +50% hunger rate
* 1.5x more likely to start a social fight
|-
| '''Malnutrition (minor)''' || 1.2 days since hunger hit zero ||
* -10% [[consciousness]]
* +60% hunger rate
* 2x more likely to start a social fight
|-
| '''Malnutrition (moderate)''' || 2.4 days since hunger hit zero ||
* -20% [[consciousness]]
* +60% hunger rate
* 2.5x more likely to start a social fight
|-
| '''Malnutrition (severe)''' || 3.5 days since hunger hit zero ||
* -30% [[consciousness]]
* +60% hunger rate
* 3x more likely to start a social fight
|-
| '''Malnutrition (extreme)''' || 4.7 days since hunger hit zero ||
* Unconscious ([[consciousness]] max. 10%)
|-
| '''Malnutrition (extreme)''' || 5.9 days since hunger hit zero ||
* [[Death]]
|}
<!-- The duration of the different symptoms are approximate -->
<!-- The exact limits are 0, 0.2, 0.4, 0.6, and 0.8 severity, with severity increasing by 0.17 per day -->

=== Blood loss ===
{{About|section=1|the effect of already lost blood|the mechanics that cause blood loss|Bleeding}}
A reduction in the normal blood volume. Minor blood loss has relatively mild effects, but as severity increases, the [[consciousness]] rapidly become debilitating. Extreme blood loss leads to [[death]]. Total blood loss is listed under whole body, with a tooltip showing the percent. 

Blood loss can occur when a pawn has untreated [[Injury#Bleeding|bleeding injuries]], has had blood harvested for [[hemogen pack]]s,{{BiotechIcon}} or has been fed on by a [[Genes#Bloodfeeder|Bloodfeeder]].{{BiotechIcon}} Blood loss from multiple sources stacks additively. 

All pawns recover 33.3% of their blood per day, regardless of [[traits]], [[genes]], [[drugs]], or [[artificial body parts]]. All natural blood recovery is stopped when a pawn is [[bleeding]], even in small amounts. Pawns can also recover through a blood transfusion operation, using 1 [[hemogen pack]]{{BiotechIcon}} to recover 35%. The [[Biosculpter_pod#Medic|biosculpter pod's medic cycle]]{{IdeologyIcon}} will also cure all blood loss, though it should be noted that non-transhumanist pawns would recover completely from blood loss in the same time as the cycle takes to complete anyway. If there is no other reason to use the medic cycle, non-transhumanist pawns should just recover outside of the pod and remain productive for that time.

{| class="wikitable"
|-
! Stage !! Begins at !! Symptoms
|-
| '''Blood loss (minor)''' || ≥15% blood loss || 
*{{--|10%}} [[Consciousness]]
|-
| '''Blood loss (moderate)''' || ≥30% blood loss || 
*{{--|20%}} [[Consciousness]]
|-
| '''Blood loss (severe)''' || ≥45% blood loss || 
*{{--|40%}} [[Consciousness]]
|-
| '''Blood loss (extreme)''' || ≥60% blood loss || 
*{{--|40%}} [[Consciousness]]
* [[Consciousness]] 10% max. (Unconsciousness)
|-
| '''Blood loss (extreme)''' || 100% blood loss || 
* [[Death]]
|}

=== Heatstroke ===
Heat stroke occurs when a pawn has prolonged exposure to [[temperature]]s 10°C (18°F) above their [[maximum comfortable temperature]], and recovery occurs in temperatures less than the maximum comfortable temperature.
Note that it is possible for a pawn to have both heatstroke and hypothermia at the same time if time is spent in both extreme heat and cold - their severities are unrelated.

Pawns additionally take periodic burn damage in temperatures more than 150°C (270°F) above their maximum comfortable temperature.
====Severity Increase====
<!-- Data from Verse/HediffGiver_Heat.cs !-->
The procedure for determining severity growth every 60-tick interval is given by:
# Take the amount by which the ambient temperature exceeds the pawn's maximum safe temperature (which is the maximum comfortable temperature +10°C).
# Pass the amount through the curve shown below to obtain the effective temperature excess. Note that for amounts from 0 to 25 °C, this doesn't result in a change.
# Multiply the excess by <code>6.45e-5</code> to obtain the severity growth this interval (60 ticks, 1 second).
# If the growth is less than <code>0.000375</code>, set it to that number. This sets a minimum amount the severity increases by for temperatures in the range of 10 to 15.814°C above the maximum comfortable temperature.
:<code>Increase in heatstroke severity every 60 ticks = max(0.000375, 0.0000645×effective_temperature_curve(<i>ambient_temperature</i> - (<i>maximum_comfortable_temperature</i> + 10°C)))</code>
::<code><i>where </i>effective_temperature_curve()<i> is a post-processing curve with points</i>: (0, 0), (25, 25), (50, 40), (100, 60), (200, 80), (400, 100), (4000, 1000).</code>
{| class="wikitable"
|-
! Effective temperature curve
|-
| {{GraphChart
|width=600
|height=150
|type=line
|showSymbols=1
|x=0, 25, 50, 100, 200, 400, 4000
|y=0, 25, 40,  60,  80, 100, 1000
|xAxisMax = 1000
|yAxisMax = 250
|xAxisTitle = Temperature excess (°C)
|yAxisTitle = Effective temperature excess
}}
|}

<div style="display:inline-table; vertical-align:top;">

{| class="wikitable"
|-class=static-row-header style=vertical-align:bottom
! Graph
! style=max-width:20em | Ambient Temperature - Maximum Comfortable Temperature (°C)
! style=max-width:15em | Growth per 60 ticks
! style=max-width:15em | Time to 100% severity (ticks)
! style=max-width:15em | Time to 100% severity (in-game time)
|-
| rowspan='9'|{{GraphChart
|width=200
|height=200
|type=line
|x=10, 12, 14, 16, 18, 20, 22, 24, 26, 28, 30, 32, 34, 36, 38, 40, 42, 44, 46, 48, 50, 52, 54, 56, 58, 60, 62, 64, 66, 68, 70, 72, 74, 76, 78, 80, 82, 84, 86, 88, 90, 92, 94, 96, 98, 100
|y=64.0, 64.0, 64.0, 62.0, 46.5, 37.2, 31.0, 26.6, 23.3, 20.7, 18.6, 16.9, 15.5, 14.5, 13.9, 13.3, 12.7, 12.2, 11.8, 11.3, 10.9, 10.6, 10.2, 9.9, 9.6, 9.3, 9.1, 8.9, 8.8, 8.6, 8.5, 8.3, 8.2, 8.0, 7.9, 7.8, 7.6, 7.5, 7.4, 7.3, 7.2, 7.0, 6.9, 6.8, 6.7, 6.6
|xAxisTitle = Ambient Temperature - Maximum Comfortable Temperature (°C)
|yAxisTitle = Time to 100% Severity (hours)
}} 
|0 || 0 || - || -
|-
| 5 || 0 || - || - 
|-
| 10 || 0.000375 || 160000 || 2.7 days
|-
| 15 || 0.000375 || 160000 || 2.7 days
|-
| 20 || 0.000645 || 93023 || 1.6 days
|-
| 25 || 0.000967 || 62016 || 1 day
|-
| 100 || 0.003612 || 16611 || 6.6 hours
|-
| 300 || 0.005386 || 11141 || 4.5 hours
|-
| 4000 || 0.064339 || 933 || 0.4 hours
|}
</div>

====Severity Decrease====
If the ambient temperature is less than the maximum comfortable temperature, the amount the severity will decrease every 60-tick interval is given by:
:<code>Decrease in heatstroke severity every 60 ticks = max(0.0015, min(0.015, 0.027×heatstroke_severity))</code>
This means that as long as the ambient temperature is less than the maximum comfortable temperature, heatstroke recovery is independent of temperature, but severity decreases at its fastest when it is above 50%, and at its slowest below 5.6%. Full recovery from near-100% severity occurs after 151 real-time seconds, or 3.6 in-game hours.
{{GraphChart
|width=200
|height=200
|type=line
|x= 0, 0.024, 0.048, 0.072, 0.096, 0.12, 0.144, 0.168, 0.192, 0.216, 0.24, 0.264, 0.288, 0.312, 0.336, 0.36, 0.384, 0.408, 0.432, 0.456, 0.48, 0.504, 0.528, 0.552, 0.576, 0.6, 0.624, 0.648, 0.672, 0.696, 0.72, 0.744, 0.768, 0.792, 0.816, 0.84, 0.864, 0.888, 0.912, 0.936, 0.96, 0.984, 1.008, 1.032, 1.056, 1.08, 1.104, 1.128, 1.152, 1.176, 1.2, 1.224, 1.248, 1.272, 1.296, 1.32, 1.344, 1.368, 1.392, 1.416, 1.44, 1.464, 1.488, 1.512, 1.536, 1.56, 1.584, 1.608, 1.632, 1.656, 1.68, 1.704, 1.728, 1.752, 1.776, 1.8, 1.824, 1.848, 1.872, 1.896, 1.92, 1.944, 1.968, 1.992, 2.016, 2.04, 2.064, 2.088, 2.112, 2.136, 2.16, 2.184, 2.208, 2.232, 2.256, 2.28, 2.304, 2.328, 2.352, 2.376, 2.4, 2.424, 2.448, 2.472, 2.496, 2.52, 2.544, 2.568, 2.592, 2.616, 2.64, 2.664, 2.688, 2.712, 2.736, 2.76, 2.784, 2.808, 2.832, 2.856, 2.88, 2.904, 2.928, 2.952, 2.976, 3.0, 3.024, 3.048, 3.072, 3.096, 3.12, 3.144, 3.168, 3.192, 3.216, 3.24, 3.264, 3.288, 3.312, 3.336, 3.36, 3.384, 3.408, 3.432, 3.456, 3.48, 3.504, 3.528, 3.552, 3.576, 3.6, 3.624
|y= 1, 0.985, 0.97, 0.955, 0.94, 0.925, 0.91, 0.895, 0.88, 0.865, 0.85, 0.835, 0.82, 0.805, 0.79, 0.775, 0.76, 0.745, 0.73, 0.715, 0.7, 0.685, 0.67, 0.655, 0.64, 0.625, 0.61, 0.595, 0.58, 0.565, 0.55, 0.53515, 0.5207, 0.50664, 0.49296, 0.47965, 0.4667, 0.4541, 0.44184, 0.42991, 0.4183, 0.40701, 0.39602, 0.38533, 0.37492, 0.3648, 0.35495, 0.34537, 0.33604, 0.32697, 0.31814, 0.30955, 0.30119, 0.29306, 0.28515, 0.27745, 0.26996, 0.26267, 0.25558, 0.24868, 0.24196, 0.23543, 0.22907, 0.22289, 0.21687, 0.21101, 0.20532, 0.19977, 0.19438, 0.18913, 0.18402, 0.17906, 0.17422, 0.16952, 0.16494, 0.16049, 0.15615, 0.15194, 0.14784, 0.14384, 0.13996, 0.13618, 0.1325, 0.12893, 0.12545, 0.12206, 0.11876, 0.11556, 0.11244, 0.1094, 0.10645, 0.10357, 0.10078, 0.09806, 0.09541, 0.09283, 0.09033, 0.08789, 0.08551, 0.0832, 0.08096, 0.07877, 0.07665, 0.07458, 0.07256, 0.0706, 0.0687, 0.06684, 0.06504, 0.06328, 0.06157, 0.05991, 0.05829, 0.05672, 0.05519, 0.05369, 0.05219, 0.05069, 0.04919, 0.04769, 0.04619, 0.04469, 0.04319, 0.04169, 0.04019, 0.03869, 0.03719, 0.03569, 0.03419, 0.03269, 0.03119, 0.02969, 0.02819, 0.02669, 0.02519, 0.02369, 0.02219, 0.02069, 0.01919, 0.01769, 0.01619, 0.01469, 0.01319, 0.01169, 0.01019, 0.00869, 0.00719, 0.00569, 0.00419, 0.00269, 0.00119, 0
|xAxisTitle = Time (hours)
|yAxisTitle = Heatstroke severity
}}
====Symptoms====
{| class="wikitable"
|-
! Stage !! Begins at !! Symptoms
|-
| '''Heatstroke (initial)''' || >0.04 Severity || 
* [[Consciousness]] -5%
|-
| '''Heatstroke (minor)'''   || >0.20 Severity || 
* [[Consciousness]] -10%
* [[Moving]] -10%
|-
| '''Heatstroke (serious)''' || >0.35 Severity || 
* [[Consciousness]] -20% 
* [[Moving]] -30%
* [[Pain]] +15%
|-
| '''Heatstroke (extreme)''' || >0.62 Severity || 
* [[Consciousness]] max. 10%
* [[Pain]] +30%
|-
| '''Heatstroke (100%)'''    || =1.00 Severity || 
* [[Death]]
|}

=== Hypothermia ===
Hypothermia occurs when a pawn has prolonged exposure to [[temperature]]s 10°C (18°F) below their [[minimum comfortable temperature]]. [[Insectoids]] don't experience hypothermia, but instead get [[hypothermic slowdown]].

Note that it is possible for a pawn to have both heatstroke and hypothermia at the same time if time is spent in both extreme heat and cold - their severities are unrelated.

<!-- Data from Verse/HediffGiver_Hypothermia.cs !-->
The rate of severity growth depends on the difference below the pawn's minimum safe temperature and the ambient temperature. The specific algorithm is:
# Take the amount by which the pawn's minimum safe temperature (which is the [[minimum comfortable temperature]] -10°C) exceeds the ambient temperature.
# Multiply the excess by <code>6.45e-5</code> to obtain the severity growth this interval. Note that unlike hyperthermia, hypothermia calculations don't use a postprocessing curve.
# If the growth is less than <code>0.00075</code>, set it to that number. As a result, temperatures between 10°C and 21.63°C less than the minimum comfortable temperature all have the same severity growth.
Expressed as a formula, this is:
:<code>Increase in hypothermia severity every 60 ticks = max(0.00075, (<i>degrees_below_comfortable</i> - 10)*0.0000645)</code>

<div style="display:inline-table; vertical-align:top;">
{| class="wikitable"
|-class=static-row-header style=vertical-align:bottom
! Graph
! style=max-width:20em | Minimum Comfortable Temperature - Ambient Temperature(°C)
! style=max-width:15em | Growth per 60 ticks
! style=max-width:15em | Time to 100% severity (ticks)
! style=max-width:15em | Time to 100% severity (in-game hours)
|-
| rowspan='8'|{{GraphChart
|width=200
|height=200
|type=line
|x = 10, 12, 14, 16, 18, 20, 22, 24, 26, 28, 30, 32, 34, 36, 38, 40, 42, 44, 46, 48, 50, 52, 54, 56, 58, 60, 62, 64, 66, 68, 70, 72, 74, 76, 78, 80, 82, 84, 86, 88, 90, 92, 94, 96, 98, 100
|y = 32.0, 32.0, 32.0, 32.0, 32.0, 32.0, 31.0, 26.6, 23.3, 20.7, 18.6, 16.9, 15.5, 14.3, 13.3, 12.4, 11.6, 10.9, 10.3, 9.8, 9.3, 8.9, 8.5, 8.1, 7.8, 7.4, 7.2, 6.9, 6.6, 6.4, 6.2, 6.0, 5.8, 5.6, 5.5, 5.3, 5.2, 5.0, 4.9, 4.8, 4.7, 4.5, 4.4, 4.3, 4.2, 4.1
|xAxisTitle = Minimum Comfortable Temperature - Ambient Temperature(°C)
|yAxisTitle = Time to 100% Severity (hours)
|yAxisMin = 0
}}
| 0 || 0 || - || -
|-
| 5 || 0 || - || - 
|-
| 10 || 0.00075 || 80000 || 32.0
|-
| 20 || 0.00075 || 80000 || 32.0
|-
| 25 || 0.000967 || 62016 || 24.8
|-
| 50 || 0.00258 || 23256 || 9.3
|-
| 100 || 0.005805 || 10336 || 4.1
|-
| 300 || 0.018705 || 3208 || 1.3
|}
</div>
Recovery from hypothermia uses the same process as recovery from heatstroke, which results in complete recovery within 3.6 in-game hours:
:<code>Decrease in hypothermia severity every 60 ticks = max(0.0015, min(0.015, 0.027×hypothermia_severity))</code>
{| class="wikitable"
|-
! Stage !! Begins at !! Symptoms
|-
| '''Hypothermia (shivering)''' || >0.04 Severity || 
* [[Consciousness]] -5%
* [[Manipulation]] -8%
|-
| '''Hypothermia (minor)'''   || >0.20 Severity || 
* [[Consciousness]] -10%
* [[Manipulation]] -20%
* [[Moving]] -10%
|-
| '''Hypothermia (serious)''' || >0.35 Severity || 
* [[Consciousness]] -20% 
* [[Manipulation]] -50%
* [[Moving]] -30%
* [[Pain]] +15%
|-
| '''Hypothermia (extreme)''' || >0.62 Severity || 
* [[Consciousness]] max. 10%
* [[Pain]] +30%
|-
| '''Hypothermia (100%)'''    || =1.00 Severity || 
* [[Death]]
|}

=== Hypothermic slowdown ===
{{quote|A special biological state used by some creatures to survive extreme cold. Instead of trying to stay warm, the creature's body chemistry adapts to prevent internal freezing despite very low temperature. Bodily functions are slowed and capacities are reduced, but the cold does no permanent damage. Some biologists call it a wakeful form of hibernation.}}

[[Insectoids]] avoid hypothermia and experience hypothermic slowdown instead with similar penalties but avoiding death at 100% and no [[frostbite]].

Slowdown value increases many times above 100% with apparently no upper limit. When defrosting insects this total value is used so defrost time is proportional to total time frozen.

<!-- Data from Verse/HediffGiver_Hypothermia.cs !-->
The rate of severity growth depends on the difference below the pawn's minimum safe temperature and the ambient temperature. The specific algorithm is:
# Take the amount by which the pawn's minimum safe temperature (which is the [[minimum comfortable temperature]] -10°C) exceeds the ambient temperature.
# Multiply the excess by <code>6.45e-5</code> to obtain the severity growth this interval. Note that unlike hyperthermia, hypothermia calculations don't use a postprocessing curve.
# If the growth is less than <code>0.00075</code>, set it to that number. As a result, temperatures between 10°C and 21.63°C less than the minimum comfortable temperature all have the same severity growth.
Expressed as a formula, this is:
:<code>Increase in hypothermia severity every 60 ticks = max(0.00075, (<i>degrees_below_comfortable</i> - 10)*0.0000645)</code>
{{GraphChart
|width=200
|height=200
|type=line
|x = 10, 12, 14, 16, 18, 20, 22, 24, 26, 28, 30, 32, 34, 36, 38, 40, 42, 44, 46, 48, 50, 52, 54, 56, 58, 60, 62, 64, 66, 68, 70, 72, 74, 76, 78, 80, 82, 84, 86, 88, 90, 92, 94, 96, 98, 100
|y = 32.0, 32.0, 32.0, 32.0, 32.0, 32.0, 31.0, 26.6, 23.3, 20.7, 18.6, 16.9, 15.5, 14.3, 13.3, 12.4, 11.6, 10.9, 10.3, 9.8, 9.3, 8.9, 8.5, 8.1, 7.8, 7.4, 7.2, 6.9, 6.6, 6.4, 6.2, 6.0, 5.8, 5.6, 5.5, 5.3, 5.2, 5.0, 4.9, 4.8, 4.7, 4.5, 4.4, 4.3, 4.2, 4.1
|xAxisTitle = Minimum Comfortable Temperature - Ambient Temperature(°C)
|yAxisTitle = Time to 100% Severity (hours)
|yAxisMin = 0
}}
<div style="display:inline-table; vertical-align:top;">
{| class="wikitable"
|-class=static-row-header style=vertical-align:bottom
! style=max-width:20em | Minimum Comfortable Temperature - Ambient Temperature(°C)
! style=max-width:15em | Growth per<br>{{ticks|60}}
! style=max-width:15em | Real Time<br>to 63% severity
! style=max-width:15em | In-Game Time<br>to 63% severity
! style=max-width:15em | Real Time<br>to 100% severity
! style=max-width:15em | In-Game Time<br>to 100% severity
|-
| 0 || 0 || - || - || - || -
|-
| 5 || 0 || - || - || - || -
|-
| 10  
| 0.075%   
| {{ticks|{{#expr: (0.63/(0.00075)) * 60}} }}
| {{#expr: (0.63/(0.00075)) * 60/2500 round 1}} hrs
| {{ticks|{{#expr: (1/(0.00075)) * 60}} }} 
| {{#expr: (1/(0.00075)) * 60/2500 round 1}} hrs
|-
| 20  
| 0.075%   
| {{ticks|{{#expr: (0.63/(0.00075)) * 60}} }} 
| {{#expr: (0.63/(0.00075)) * 60/2500 round 1}} hrs 
|  {{ticks|{{#expr: (1/(0.00075)) * 60}} }} 
| {{#expr: (1/(0.00075)) * 60/2500 round 1}} hrs
|-
| 25  
| {{#expr: (25-10)*0.0000645 * 100}}%
| {{ticks|{{#expr: (0.63/(( 25-10)*0.0000645)) * 60 round 0}} }} 
| {{#expr: (0.63/(( 25-10)*0.0000645)) * 60/2500 round 1}} hrs 
| {{ticks|{{#expr: (1/(( 25-10)*0.0000645)) * 60 round 0}} }} 
| {{#expr: (1/(( 25-10)*0.0000645)) * 60/2500 round 1}} hrs
|-
| 50  
| {{#expr: (50-10)*0.0000645 * 100}}%
| {{ticks|{{#expr: (0.63/(( 50-10)*0.0000645)) * 60 round 0}} }} 
| {{#expr: (0.63/(( 50-10)*0.0000645)) * 60/2500 round 1}} hrs
| {{ticks|{{#expr: (1/(( 50-10)*0.0000645)) * 60 round 0}} }} 
| {{#expr: (1/(( 50-10)*0.0000645)) * 60/2500 round 1}} hrs
|-
| 100 
| {{#expr: (100-10)*0.0000645 * 100}}%
| {{ticks|{{#expr: (0.63/((100-10)*0.0000645)) * 60 round 0}} }} 
| {{#expr: (0.63/((100-10)*0.0000645)) * 60/2500 round 1}} hrs
| {{ticks|{{#expr: (1/((100-10)*0.0000645)) * 60 round 0}} }} 
| {{#expr: (1/((100-10)*0.0000645)) * 60/2500 round 1}} hrs
|-
| 300 
| {{#expr: (300-10)*0.0000645 * 100}}%
| {{ticks|{{#expr: (0.63/((300-10)*0.0000645)) * 60 round 0}} }} 
| {{#expr: (0.63/((300-10)*0.0000645)) * 60/2500 round 1}} hrs
| {{ticks|{{#expr: (1/((300-10)*0.0000645)) * 60 round 0}} }} 
| {{#expr: (1/((300-10)*0.0000645)) * 60/2500 round 1}} hrs
|}
</div>
Recovery from hypothermia uses the same process as recovery from heatstroke, which results in complete recovery within 3.6 in-game hours:
:<code>Decrease in hypothermia severity every 60 ticks = max(0.0015, min(0.015, 0.027×hypothermia_severity))</code>
{| class="wikitable"
|-
! Stage !! Begins at !! Symptoms
|-
| '''Hypothermic slowdown (minor)''' || >0.04 Severity || 
* [[Consciousness]] -5%
* [[Moving]] -8%
|-
| '''Hypothermic slowdown (moderate)'''   || >0.20 Severity || 
* [[Consciousness]] -20%
* [[Moving]] -20%
* [[Manipulation]] -20%
* Hunger rate -10%
|-
| '''Hypothermic slowdown (serious)''' || >0.35 Severity || 
* [[Consciousness]] -40% 
* [[Moving]] -40%
* [[Manipulation]] -50%
* Hunger rate -40%
|-
| '''Hypothermic slowdown (extreme)''' || >0.62 Severity || 
* [[Consciousness]] max. 10%
* Hunger rate -95%
|}

== Pregnancy ==
{{See also|Animals#Mating{{!}}Mating|Animals#Breeding{{!}}Breeding|Reproduction{{!}}Human pregnancy}}
{{quote|This creature is gestating offspring. It will give birth if the pregnancy comes to term. If starved or injured, there may be a miscarriage.|Description}}

Tamed, non-[[human]], non-[[insectoid]], non-[[egg]]laying, female [[animals]] have a 50% chance to get pregnant from [[Animals#Mating|mating]]. While this is not an ailment in the traditional sense, it does have mechanical effects. For the first {{ticks|600}} this condition will be invisible, after which point a message will come up mentioning the pregnancy.

Humans can be pregnant only if the [[Biotech DLC]]{{BiotechIcon}} is enabled. They have a different list of symptoms. See [[Reproduction]] for details.

A pregnant animal suffering from [[malnutrition]] of 25% or higher or that is injured may miscarry. Miscarriages are noted by an in-game message. 

Some animals will give birth to multiple young. The probability of this is determined by a curve, and is different for each animal. 

The duration, and thus the severity gain per day, depends on the gestation time of the animal in question.
{| class="wikitable"
|-
! Stage !! Begins at !! Symptoms
|-
| '''Early-stage''' || >0 Severity ||
* [[Vomiting]] (''MTB of 2.5 days'')
|-
| '''Middle-stage''' || >0.333 Severity ||
* {{--|15%}} [[Moving]]
|-
| '''Late-stage''' || >0.666 Severity||
* [[Vomiting]] (''MTB of 5 days'')
* {{--|30%}} [[Moving]]
|-
| '''''Birth''''' || 1.0 Severity||
* Symptoms end
* Offspring is born
|}

=== Sterilized ===
{{Stub|section=1|reason=Missing details, sources, mechanics etc. Are there any other causes in humans?}}
{{Quote|This creature's reproductive system has been permanently shut down.|Description}}
[[Animals]] can be sterilized by use of the "Sterilize" [[operation]] to prevent them from being able to reproduce, and the sterilized animal won't attempt to mate with others nor will others attempt to mate with it. [[Egg]] laying animals will stop laying eggs when sterilized. The animal acts as normal in all other ways, including [[milk]] production. 

The sterilization operation requires [[Medical]] skill of 3 and {{ticks|500}} of work.

Humans with the "Sterilized" health trait can only be healed with a [[healer mech serum]]. Male humans can{{Check Tag|Will?|Is it all failures or just a chance?}} receive the sterilized ailment from a failed vasectomy.{{BiotechIcon}} It is currently unknown if there are other sources or if female humans can be affected.

== Drug damage ==
These ailments are caused by excess drug use.

=== Cirrhosis ===
A degenerative liver disease caused by excessive alcohol consumption.
An otherwise healthy pawn with cirrhosis will have an [[immunity gain speed]] of 70%, making them extremely vulnerable to disease.

{| class="wikitable"
|-
! Ailment !! Symptoms
|-
| '''Cirrhosis''' || 
* -60% part efficiency (liver)
* Slight [[pain]] (+15%)
* -10% [[Moving]]
|}

Treatment:
* The easiest method of treatment is the transplantation of a new liver. Due to the extreme vulnerability to disease, even if your colony dislikes organ harvesting it may be worth it to replace the livers of valuable pawns as doctors will struggle to get high enough tend qualities on diseases to counterbalance the decreased immunity gain, often needing a very good hospital plus a very good doctor or glitterworld medicine to do so.
* Other than transplantation, only healer mech serum and resurrector mech serum can cure cirrhosis, including any DLC added healing methods.{{Check Tag|Fact Check|Needs to be verified that this is the only way to cure it. What about Luciferium for instance?}}

=== Chemical damage ===
Permanent damage that occurs as a result of drug overdose or tolerance. There are two variants.

{| class="wikitable"
|-
! Ailment !! Symptoms
|-
| '''Chemical damage (moderate)''' || 
* -50% part efficiency
* Always applied to the brain
|-
| '''Chemical damage (severe)''' || 
* -80% part efficiency
* Always applied to the kidneys
|}

Treatment:
* Kidney chemical damage can be cured by replacing with a non-damaged [[kidney]] or with a [[detoxifier kidney]]{{BiotechIcon}}
* Brain chemical damage can only be cured with a [[healer mech serum]]{{Check Tag|Fact Check|Needs to be verified that this is the only way to cure it.}}

==Trauma savant==
Injuries to the brain can cause increased motor function, but loss of social capabilities.
{| class="wikitable"
|-
! Ailment !! Symptoms
|-
| '''Trauma savant''' || 
* +50% [[Manipulation]]
* x0% [[Talking]] and [[Hearing]]
* Brain damage does not affect part efficiency
* Nullifies all opinions of other pawns
|}

The chance to receive trauma savant on any physical (non-chemical) [[injury]] to the brain is equal to the percentage of the brain damaged multiplied by 0.12. For an adult human, this represents 1.2% chance per point of damage. Animals can also become trauma savants. 

A [[Ghoul|Ghoul]]{{AnomalyIcon}} or a humans with the [[Scarless]]{{BiotechIcon}} gene will not get brain scars from damage to their brain, but they still have a chance to become trauma savants. This makes it possible to voluntarily give the condition to a pawn by repeatedly damaging and healing their brain, although this can be time consuming and expensive. For an adult human, the brain will need to take on average 83 points of damage. Using other methods to heal the brain such as the [[Biosculpter pod#Bioregeneration|Bioregeneration cycle]] of the [[biosculpter pod]]{{IdeologyIcon}} is theoretically possible, but prohibitively expensive. 

Note that while trauma savant does negate the [[consciousness]] penalty from all brain damage (even from scars that didn't cause savant to appear), it does not negate the missing health, or the potential pain from the scar. To treat those problems, you must treat the brain damage itself. It also won't prevent loss of consciousness from other conditions like Dementia. 

Trauma savant can be healed with a [[healer mech serum]] or the [[Creepjoiner#Unnatural_healing|Unnatural healing]]{{AnomalyIcon}} ability if no other medical condition is present. It can also be treated by killing the pawn, [[Skull|removing their skull]]{{IdeologyIcon}} then resurrecting thanks to a [[Resurrector mech serum]] or [[death refusal]]{{AnomalyIcon}}.

== General ==
These ailments appear in gameplay, and usually wear off on their own (except death-causing ones).

=== Cryptosleep sickness ===
After-effects of using a cryptosleep pod. Cryptosleep suspends and replaces many bodily functions in order to prevent aging and death. Upon exiting cryptosleep, the body takes time to restart and rebalance its natural metabolic processes. While this is ongoing, the patient suffers from nausea, dizziness, and a sense of fuzziness in the mind.

Occurs after having been in a [[ship cryptosleep casket]] or a [[cryptosleep casket]] for any amount of time. The colonists in the "[[Scenario system#Crashlanded|Crashlanded]]" scenario have a chance of starting with cryptosleep sickness, as they were in cryptosleep before crashing on the planet.

{| class="wikitable"
|-
! Ailment !! Symptoms
|-
| '''Cryptosleep sickness''' || 
* Frequent [[vomiting]] (''MTB of 3 hours'')
* Impaired [[consciousness]] (×80%)
* Impaired [[moving]] (×90%)
* Impaired [[manipulation]] (×90%)
|}
Treatment:
* Wears off after {{ticks|10000}}

=== Food poisoning ===
Occurs after eating a contaminated meal or occasionally from raw food. The chance of contamination for cooked meals is determined by the [[Room stats#Cleanliness|cleanliness of the room]] where it was prepared and cook's [[food poison chance]] stat. 

Raw food has a flat 2% chance of giving food poisoning, while [[corpse]]s have a flat 5% chance. Cooked meals roll two separate probabilities to determine if the food is poisoned. The first checks the [[cleanliness]] of the kitchen used. See the accompanying graph for specifics. Note that cleanliness above -2 prevents this roll from producing poisoned meals. If the cooking station is outdoors, the default chance is 2%. 

If the first roll fails to poison the meal, then a second roll is performed, this time based on the [[food poison chance]] of the pawn, controlled entirely by their [[Skills#Cooking|cooking skill]].
If the second roll indicates that the meal is poisonous, the probability of poisoning the pawn is 100% for that individual meal. However, when the poisonous meal is part of a stack with other meals, the probability is distributed among all the meals in the stack. This distribution reduces the chance of food poisoning from 100% to the ratio of total meals to poisonous meals within the stack. For instance, if a poisonous meal is placed on top of a stack containing three non-poisonous meals, the probability for each meal to poison the pawn becomes 25%. Consequently, even if the original meal was poisonous, there is a possibility that no pawns will experience food poisoning.
:{| class = "wikitable" width="180"
! Cooking Skill&nbsp;Level
! Chance from Skill&nbsp;Level
! Chance from Room Cleanliness
|- 
| style="background-color:#F00000" align="center" | 0 || style="background-color:#F00000" align="center" | 5.00% || rowspan="10"| {{GraphChart|width=400|height=100|type=line|x=-5, -3.5, -2, 0|y=5, 2.5, 0, 0|xAxisTitle=Room Cleanliness|yAxisTitle=Food Poisoning Chance (%)}}
|- style="background-color:#FF5500"
| align="center" | 1 || align="center" | 4.00%
|- style="background-color:#FBA933"
| align="center" | 2 || align="center" | 3.00%

|- style="background-color:#E3C933"
| align="center" | 3 || align="center" | 2.00%
|- style="background-color:#E3E933"
| align="center" | 4 || align="center" | 1.50%
|- style="background-color:#C3FF33"
| align="center" | 5 || align="center" | 1.00%

|- style="background-color:#B6FF00"
| align="center" | 6 || align="center" | 0.50%
|- style="background-color:#86FF00"
| align="center" | 7 || align="center" | 0.25%
|- style="background-color:#66FF00"
| align="center" | 8 || align="center" | 0.15%

|- style="background-color:#00FF00"
| align="center" | 9-20 || align="center" | 0.10%
|}

; Symptoms and progress:
Food poisoning lasts 24 hours with no after-effects. It has 3 stages: the first unpleasant 4 hours, followed by a crippling 16 hours, and finally an unpleasant 4 hours largely similar to the first stage, as described in the table below.
:{| class="wikitable"
|-
! Stage !! Begins at !! Symptoms
|-
| '''Food poisoning (initial)''' || 0–4 hours from onset ||
* [[Vomiting]] (''MTB of 0.3 days'')
* Some [[pain]] (+20%)
* Impaired [[consciousness]] (×60%)
* Impaired [[moving]] (×80%)
* Impaired [[manipulation]] (×90%)
* Reduced [[blood filtration]] (×95%)
* Much slower [[Eating speed|eating]] (×50%)
|-
| '''Food poisoning (major)''' || 4–20 hours from onset ||
* [[Vomiting]] (''MTB of 0.2 days'')
* Significant [[pain]] (+40%)
* Impaired [[consciousness]] (×50%)
* Impaired [[moving]] (×50%)
* Impaired [[manipulation]] (×80%)
* Reduced [[blood filtration]] (×85%)
* Slower [[Eating speed|eating]]  (×30%)
|-
| '''Food poisoning (recovering)''' || 20–24 hours from onset ||
* [[Vomiting]] (''MTB of 0.4 days'')
* Some [[pain]] (+20%)
* Impaired [[consciousness]] (×60%)
* Impaired [[moving]] (×80%)
* Impaired [[manipulation]] (×90%)
* Reduced [[blood filtration]] (×95%)
* Slower [[Eating speed|eating]]  (×50%)
|}
; Treatment and Prevention
Food poisoning can only minimized by manipulating the factors that cause it mentioned above. Prevention can only be guaranteed by exclusively consuming meals purchased from traders or [[nutrient paste meal]]s as they will never cause food poisoning, or by installing a [[sterilizing stomach|sterilizing]] {{RoyaltyIcon}} or [[nuclear stomach]] {{RoyaltyIcon}} or having the [[strong stomach]] gene{{BiotechIcon}} which renders the pawn immune. 

There is no practical treatment for food poisoning, you simply have to let it run its course. [[Healer mech serum]] will cure it (if there is nothing worse to cure), but this costly measure is rarely if ever worthwhile, as food poisoning only affects the pawn for the 24 hour cycle and then leaves them as healthy as they were before.

Because of the high chance of [[vomiting]] at any moment, putting the patient on a temporary diet of [[pemmican]] may be an useful. Vomiting interrupts the process of eating, resetting it to the start, but a colonist can more quickly consume several pieces of pemmican between "attacks" that they can eat an entire [[meal]]. This allows the poisoned pawn to more easily avoid malnutrition without feeding them [[raw food]]s that could cause further poisoning.

Because of the penalty to [[blood filtration]] and [[consciousness]], food poisoning in combination with other ailments such as an [[infection]] can be a cause for concern.

=== Toxic buildup ===
{{Stub|section=1|reason=What is the effect of Toxic Environment Resistance vs Toxic Resistance}}
Primarily occurs with exposure to [[Events#Toxic fallout|toxic fallout]], [[pollution]],{{BiotechIcon}} and [[tox gas]].{{BiotechIcon}}. Prolonged exposure gradually increases the buildup severity. 

Alternatively, some attacks cause instantaneous increases in toxic buildup severity, such as [[cobra]] and [[waste rat]] {{BiotechIcon}} bites, the [[venom talon]] {{RoyaltyIcon}}, or [[venom fangs]] {{RoyaltyIcon}}. 

A colonist under a roof is protected from toxic fallout, and avoiding interaction with the other sources can prevent buildup from them. If they are exposed to the fallout, they will accumulate Toxic Buildup at a rate of 40% per day. Pollution will accumulate at the same rate, but cannot be mitigated through roofing. When walking through polluted terrain in [[caravan]]s, they will accumulate buildup at 20% per day in Moderately Polluted terrain (50%-75% polluted tiles) and 40% per day in Extremely Polluted terrain (above 75%). Buildup from both pollution as well as toxic fallout can stack, meaning a pawn standing in polluted terrain while a toxic fallout can gain 80%/day.

This buildup severity gained is proportional to the [[Toxic Resistance]] [[stat]] - thus, [[human]]s buildup at the full rate, [[animal]]s at half, and [[insects]] and [[mechanoids]] are immune.{{Check Tag|Body Size?|Buildup severities from Damage types are now inversely proportional to body size, are all sources scaled? Either way, add detail}} Buildup can also be reduced through a variety of of other means including items such as the [[gas mask]] {{BiotechIcon}}, [[detoxifier kidney]] {{BiotechIcon}}, and [[detoxifier lung]] {{BiotechIcon}}, as well as [[genes]] such as [[Genes#Partial antitoxic lungs|Partial antitoxic lungs]] and [[Genes#Total antitoxic lungs|Total antitoxic lungs]], or [[Genes#Tox resistance|Tox resistance]] and [[Genes#Tox immunity|Tox immunity]].

There is, effectively, a multiplier for each pawn on their toxic buildup accumulation from these indirect sources. This can vary between 15% faster buildup or 15% slower buildup than the average rate. There is no stat in the information panel to convey this variation, but it is static for a given pawn. This means that baseliner humans standing in pollution and a toxic fallout, with no Tox Resistance of any sort, can vary from either 68% to 92% buildup per day, rather than a constant 80%.

The buildup severity occurs in stages. The later stages cause permanent [[#Dementia|dementia]] which does not wear off even after toxic buildup subsides. When a pawn affected by toxic buildup [[Death|dies]], there is a chance that its corpse will instantly rot - this chance is equal to the severity.

Once a colonist returns to a safe area, such as a roofed area for toxic fallout, or otherwise stops taking severity increases, their buildup severity will gradually decrease. Once no longer exposed, severity reduces by 8% per day, meaning that it will take up to 12.5 days to eliminate all toxins accumulated in the body. However, colonists that reach high stages of toxic buildup are likely to develop further complications.
{| class="wikitable"
|-
! Stage !! Begins at !! Symptoms
|-
| '''Toxic buildup (initial)''' || ≥4% severity ||
* -5% [[Consciousness]]
|-
| '''Toxic buildup (minor)''' || ≥20% severity ||
* -10% [[Consciousness]]
|-
| '''Toxic buildup (moderate)''' || ≥40% severity ||
* -15% [[Consciousness]]
* [[Vomiting]] (''MTB of 5 days'')
* [[Dementia]] ('''permanent''', ''MTB of 146 days to develop'')
* [[Carcinoma]] (''MTB of 438 days to develop'')
|-
| '''Toxic buildup (serious)''' || ≥60% severity ||
* -25% [[Consciousness]]
* [[Vomiting]] (''MTB of 1 day'')
* [[Dementia]] ('''permanent''', ''MTB of 37 days to develop'')
* [[Carcinoma]] (''MTB of 111 days to develop'')
|-
| '''Toxic buildup (extreme)''' || ≥80% severity ||
* Unconsciousness (Max. [[consciousness]] 10%)
* [[Vomiting]] (''MTB of 0.5 day'')
* [[Dementia]] ('''permanent''', ''MTB of 13 days to develop'')
* [[Carcinoma]] (''MTB of 39 days to develop'')
|-
| '''Toxic buildup (extreme)''' || 100% severity ||
* [[Death]]
|}

=== Brain shock ===
{{quote|"After-effects of an electrical shock to the brain. This is generally cause by feedback from brain implants hit by EMP pulses."  - '''In-game description'''}}
Occurs when an [[EMP]] effect hits a pawn with the following brain implants:
* [[Learning assistant]] {{RoyaltyIcon}}
* [[Neurocalculator]] {{RoyaltyIcon}}
* [[Circadian assistant]] {{RoyaltyIcon}}
* [[Circadian half-cycler]] {{RoyaltyIcon}}
It lasts between {{ticks|2500}} and {{ticks|3500}}.

Despite only occurring with implants from the [[Royalty DLC]], it is defined in the core code.

{| class="wikitable"
|-
! Stage !! Symptoms
|-
| '''Brain shock''' ||
* Unconscious ([[Consciousness]] max. 10%)
|}

=== Psychic shock ===
{{quote|A state of psychic chaos in the brain and mind. Caused by psychic attacks or critical level of neural heat, this effect is debilitating until it wears off.|In-game description}}
Occurs when a pawn is hit by the effect of a [[psychic shock lance]] or when exceeding a pawn's [[Psycasts#Psycasts#Neural heat limit|neural heat limits]] when psycasting {{RoyaltyIcon}}.

It lasts {{ticks|7500}}.

{| class="wikitable"
|-
! Stage !! Symptoms
|-
| '''Psychic shock''' ||
* Unconscious ([[Consciousness]] max. 10%)
|}

=== Psychic coma ===
{{quote|"A form of benign coma during which the brain recovers from a psychic overload."|In-game description}}
A coma inflicted by certain [[psycasts]]{{RoyaltyIcon}} including:
* [[Neural heat dump]], lasting 1 day.
* [[Neuroquake]], lasting 5 days.
* [[Word of Serenity]], lasting 6 hours with duration scaling with [[psychic sensitivity]].
Note that despite only being caused by psycasts from the [[Royalty DLC]], the hediff itself is defined in Core. 

It has the following effects:
* [[Consciousness]]: {{Bad|10%}} Max.

=== Psychic breakdown ===
{{Royalty|section=1}}
{{Stub|section=1|reason=Unknown whether should remain on [[Psycasts]], whether it should be moved here, or whether a transclusion or template should be used to duplicate it in both places}}
{{Main|Psycasts#Psychic_breakdown|l1=Psychic breakdown}}

=== Biosculpting sickness ===
{{Ideology|section=1}}
{{quote|"The after-effects of an incomplete biosculpting cycle. It causes nausea, dizziness, and fuzzy thinking."|In-game description}}
Occurs when a pawn is ejected early from a [[biosculpter pod]] either manually or as a result of 24 hours without power.

It lasts between {{ticks|8000}} and {{ticks|12000}}

{| class="wikitable"
|-
! Stage !! Symptoms
|-
| '''Biosculpting sickness''' ||
* [[Consciousness]] ×80%
* [[Moving]] ×90%
* [[Manipulation]] ×90%
* [[Vomiting]] (Mtb 0.125 days)
|}

=== Scanning sickness ===
{{Biotech|section=1}}
{{quote|"This person was scanned by a softscanner to produce a mechanoid subcore. The high-energy scanning device has caused disturbances in their brain chemistry which will take time to resolve themselves. There won't be any long-term damage."|In-game description}}
A person scanned in a [[subcore softscanner]] to produce a [[standard subcore]] is afflicted with scanning sickness starting with a severity of 4 and decreasing in severity by 1 per in-game day.{{Check Tag|Mechanitor Factor?|Mechanitor factor of 2 is detailed in the severity per day section of the code. What is this? Does it mean Mechanitors reduce in severity 2x as fast? Etc.}} This has the following effects:
* [[Consciousness]]: {{Bad|x75%}} (Post factors)
* [[Manipulation]]: {{Bad|x75%}} (Post factors)
* [[Moving]]: {{Bad|x75%}} (Post factors)
* [[Vomiting]] {{MTB}}: {{Bad|1.5 days}}
* [[Mood]]: {{--|8}}

=== Bio-starvation ===
{{Biotech|section=1}}
{{quote|"This person was in a growth vat which wasn't functioning properly due to lack of power or nutrition feedstock. This has left their body in a state of bio-starvation."|In-game description}}
A pawn in a [[growth vat]] with no power or nutrition, will enter [[bio-starvation]], increasing in severity by 50% per day starved, and decreasing 10% per day properly supplied or spent outside the vat. Bio-starvation increases nutrition consumption in a vat by {{bad|+10%}} at all severities, and [[Death|kills]] at 100%. If a bio-starved pawn leaves the vat, a number of status effects will be applied to them. These include:
* [[Pain]]: {{++|15%}}
* [[Hunger Rate Factor]] offset: {{++|50%}}
* [[Consciousness]]: {{--|25%}}

=== Vomiting ===
{{Stub|section=1|reason=what does it interrupt, what happens when different tasks are underway - e.g. eating cancels the eating task but doesn't waste the meal, explanation that vomiting is expressed as mtb etc}}
The body attempting to forcefully expunge toxins. Unfortunately for your pawns, this doesn't work in Rimworld.

Vomiting is caused by a wide variety of ailments{{Check Tag|List Needed?}}, some [[Psycasts]]{{RoyaltyIcon}}, or being hit with an EMP while having the [[Sterilizing stomach|Sterilizing]], [[Reprocessor stomach|Reprocessor]], or [[Nuclear stomach|Nuclear]] stomachs{{RoyaltyIcon}} installed.

A pawn that is vomiting will stop in place, face the side, and begin vomiting. The process takes away .05 nutrition over 3-5 ticks{{Check Tag|Verify|I just vaguely recall this from watching it, someone please check my numbers. I also have no idea if body size changes nutrition lost}}, and causes 3-5 piles of [[Vomit]] to appear on the tile they're facing. A pawn lying in a bed will not stand up to vomit{{Check Tag|Details|Does this pause the resting bonus from lying down? Does it wake them up?}}.

Vomiting will interrupt most tasks, including eating, walking, aiming a weapon, or working at a station, but they will resume the task once they stop vomiting{{Check Tag|Mechanics|Do pawns who are actively vomiting still reserve the task they were working on?}}. For this reason, it is recommended that pawns who are afflicted with an ailment that causes frequent vomiting, such as [[food poisoning]], eat foods like [[pemmican]], as a pawn who vomits while in the middle of eating a normal meal will lose all progress towards consuming it (note that the meal is not wasted), but a pawn eating pemmican will still consume part of the stack. Similarly, they should also avoid long tasks that have their progress reset on being interrupted, such as cooking 4x [[lavish meal]]s.

== Surgical ==
These ailments happen with medical operations.

=== Anesthetic ===
Used in surgery to make sure that a pawn is unconscious. It can also be administered outside of operations using a medical bill, consuming medicine.

A pawn under anesthesia is unconscious for the first 6 hours, and the worst effects of anesthetic wear off after 12 hours, so arranging operations to be performed some time just before a pawn needs to sleep is recommended if you want them functioning the next work day.

{| class="wikitable"
|-
! Stage !! Begins at !! Symptoms
|-
| '''Anesthetic (sedated)''' || 0–6 hours from onset ||
* Unconscious ([[Consciousness]] max. 1%)
|-
| '''Anesthetic (woozy)''' || 6–12 hours from onset ||
* Reduced [[pain]] (×80%)
* Impaired [[consciousness]] (70% max)
* Impaired [[moving]] (-20%)
* Impaired [[manipulation]] (-20%)
* Impaired [[digestion]] (-20%
* Impaired [[sight]] (-15%)
* [[Vomiting]] (''MTB of 0.25 days'')
* Confused wandering (''MTB of 5 days'')
* Forget memory thought (''MTB of 5 days'')
* Improved [[mood]] (+10)
|-
| '''Anesthetic (wearing off)''' || 12+ hours from onset ||
* Reduced [[pain]] (×95%)
* Impaired [[consciousness]] (90% max)
* Impaired [[moving]] (-5%)
* Impaired [[manipulation]] (-10%)
* [[Vomiting]] (''MTB of 4 days'')
* Confused wandering (''MTB of 50 days'')
|}

Treatment:
* Wears off on its own between {{ticks|45000}} to {{ticks|75000}} even if severity has not reached 0%
** Surgery is unaffected even if it wears off before finished

==== Version history ====
Prior to 1.1 it lasted only {{ticks|15000}} and did not have any other stages afterwards.

== Resurrection ==
These may occur after a dose of [[resurrector mech serum]] is applied on a [[Death|dead]] pawn.

=== Resurrection sickness ===
After-effects of being resurrected by mechanite injection. Artificially-kickstarted body processes take time to rebalance themselves.

{| class="wikitable"
|-
! Ailment !! Symptoms
|-
| '''Resurrection sickness''' || 
* Loss of [[moving]] (×10%)
* Loss of [[manipulation]] (×10%)
* [[Vomiting]] (mtb. 0.5 days)
|}

'''Treatment:'''
* Wears off anywhere from {{ticks|90000}} to {{ticks|150000}}

'''Probability:'''
* 100% chance of being applied

=== Blindness ===
Mechanites fail to properly repair the eyes, instead causing more damage to it, resulting in blindness.

Blindness from [[resurrector mech serum]] applies to both eyes, resulting in total blindness

{| class="wikitable"
|-
! Ailment !! Symptoms
|-
| '''Blindness''' || 
* Complete loss of function (-100% part efficiency)
|}

'''Treatment:'''
* Replace eyes with [[bionic eye]]s or [[archotech eye]]s

'''Probability:'''
* 2% chance when used at 0.1 days or less of decay
* Linearly increases to 80% after 5 days decayed

=== Resurrection psychosis ===
Chaotic thought patterns caused by the decoherence of resurrection mechanites. Resurrection psychosis progresses and eventually causes total psychosis and [[death]].

The severity of the psychosis increases by 0.01 per day, meaning that it will kill in 100 days after resurrection, or 90 days after this ailment becoming visible. Hopefully this gives you enough time to find a [[healer mech serum]] to heal the ailment, find another [[resurrector mech serum]] to attempt the resurrection again once the psychosis has run its course, or build a [[cryptosleep casket]] to give you time to find either serum. There are no other ways to cure the disease.

{| class="wikitable"
|-
! Stage !! Begins at !! Symptoms
|-
| '''Resurrection psychosis (hidden)''' || ≥0% severity ||
* No visible symptoms, doesn't show up in health tab
* Can still be cured with [[healer mech serum]] at this stage even if it is not visible.
|-
| '''Resurrection psychosis (early)''' || ≥10% severity ||
* Frequent mental breaks (''MTB of 9 days'')
|-
| '''Resurrection psychosis (moderate)''' || ≥25% severity ||
* [[Consciousness]] -10%
* Frequent mental breaks (''MTB of 6 days'')
|-
| '''Resurrection psychosis (advanced)''' || ≥40% severity ||
* [[Consciousness]] -20%
* Frequent mental breaks (''MTB of 3 days'')
|-
| '''Resurrection psychosis (severe)''' || ≥55% severity ||
* [[Consciousness]] -30%
* Extremely frequent mental breaks (''MTB of 0.5 days'')
|-
| '''Resurrection psychosis (total)''' || ≥70% severity ||
* [[Consciousness]] -40%
* Extremely frequent mental breaks (''MTB of 0.25 days'')
|-
| '''Resurrection psychosis (catatonic)''' || ≥85% severity ||
* Pawn becomes unconscious ([[Consciousness]] max. 10%)
|-
| '''Resurrection psychosis (catatonic)''' || 100% severity ||
* [[Death]]
|}

'''Treatments:'''
* Healer mech serum
* Allowing the pawn to [[Death|die]] again, then resurrecting once more (rerolls the disease)

'''Probability of contracting:'''
* 2% chance when used at 0.1 days or less of decay
* Linearly increases to 80% after 5 days decayed

'''Prevention:'''
* Freeze corpses immediately after death.  Corpses placed in a [[sarcophagus]] are still affected by the temperature of the room they are in, and can be removed later but are protected from butchering, hungry animals and assuming you build the sarcophagus from something [[Flammability|non-flammable]], [[fire]].

== Heart attack ==
Heart attacks can randomly occur on any pawn/animal at any time, but they become more frequent as they pass half of their life expectancy (e.g. 40 years in humans), triggered by the [[Events#Birthday|birthday event]]. There must be more than 2 colonists on your colony for this to occur.

The average interval between heart attacks is curved as follows (in days):
* 0-50% of life expectancy: 99,999,999 - 99,999,999
* 50-60% of life expectancy: 99,999,999 - 2,500
* 60-100% of life expectancy: 2,500 - 300

Examples of intervals and chances:
* 55% of life expectancy (i.e. 44 in humans): 50,001,249.5 days (approx. 0.00000002% per day)
* 80% of life expectancy (i.e. 64 in humans): 1,400 days (approx. 0.000714% per day)

=== Stages ===
{| class="wikitable"
|-
! Stage !! Begins at !! Symptoms
|-
|'''Painful''' || 0% Severity || 
* [[Consciousness]] ×50%
* [[Pain]] +40%
|-
|'''Debilitating''' || 60% Severity || 
* [[Consciousness]] max. 10% (Unconsciousness)
* [[Pain]] +60%
|-
|'''Fatal''' || 100% Severity || 
* [[Death]]
|}

==== Progression ====
Heart attacks always start at 40% severity. Every {{ticks|5000}} the heart attack severity will randomly change by a value between -40% to +60%. This means that it is possible for a heart attack to treat itself on its own, but usually the heart attack progresses to fatal severity.

==== Treatment ====
Like injuries, medicine can be used to treat a heart attack. 

Doctors treating heart attacks will administer treatments rapidly, consuming medicine in the process. Each treatment has a chance to succeed, reducing the heart attack severity by 30%. Successfully reducing severity below 0 will completely treat the heart attack. 

The maximum chance a particular treatment can succeed is 65%.

==== Prevention ====
Replacing a pawn's heart with either a [[prosthetic heart|prosthetic]] or [[bionic heart]] will completely prevent heart attacks. Note however that while the bionic heart improves the [[blood pumping]] capacity, the  prosthetic heart decreases it, and thus all of the stats and capacities it affects.

== Version history ==
* [[Version/0.7.581|0.7.581]] Added with cataracts and bad back
* [[Version/0.8.657|0.8.657]] - Added hypothermia, frostbite, heatstroke, and burns from being in areas with extreme temperatures.
* [[Version/0.9.722|0.9.722]] - Food poisoning and cryptosleep sickness added. Some ailments can now cause vomiting.
* [[Version/0.10.785|0.10.785]] - Starvation and blood loss are now staged and affect consciousness as they worsen.
* [[Version/0.12.906|0.12.906]] - All organisms including animals have life expectancies and will develop chronic conditions like frailty or cataracts in old age. Heart attacks added.
* [[Version/0.13.1135|0.13.1135]] - Carcinoma, asthma, and hearing loss added.
* [[Version/1.0.0|1.0.0]] - Minor starvation (below 25% severity) no longer causes miscarriages.
* [[Version/1.1.0|1.1.0]] - Pregnant animal is no longer viewed as sick because pregnancy affects its capacities. and thus now sells for the same as one with no health conditions.
* [[Version/1.3.3117|1.3.3117]] - Extreme blood loss now reduces consciousness by 40% in addition to setting the capacity's max to 10%. Prior to this, pawns could nonsensically [[Death|die]] by healing from extreme to severe bloodloss if their consciousness was below 40% from other symptoms - extreme would simply max it at 10% but healing to severe would reduce it by 40% to 0% and kill the pawn. 
* [[Version/1.4.3523|1.4.3523]] - Sterilized animals no longer lay eggs.

[[Category:Health]]